Siegrune and Brynhild are next-gen Gun Bullet Children, created by being fused with angels, almost to the point of death. They possess overwhelming powers, but the price is that their hearts and minds have become twisted.
Together, they are able to summon the most powerful of the magical beasts, Fenris Wolf, to possess their bodies and they can tap into his boundless magical powers.
This was formerly Siegrune’s power alone, but it proved too difficult to control and so the Church brought it under control by transfusing half of the power into Brynhild.